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大量动物实验和初步的临床观察表明,鼠源性McAb有可能成为一些病毒性疾病特异而有效的治疗制剂。其作用机理主要是对病毒的直接中和而抑制感染,也可通过介导机体的CDC和/或ADCC效应而发挥作用。在将鼠源性McAb普遍应用于临床之前,尚需对其药代动力学及其可能的副作用等进行深入研究。
A large number of animal experiments and preliminary clinical observations show that murine McAbs may be some viral diseases specific and effective therapeutic agents. Its mechanism of action is mainly direct neutralization of the virus and inhibit infection, but also through the body’s CDC and / or ADCC effect and play a role. In the general application of murine McAb in clinical, its pharmacokinetics and its possible side effects need to be further studied.