Two Cases of ANCA-negative Pauci-immune Crescentic Glomerulonephritis in Pregnant or Maternal Women

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Here two cases of renal failure occurring in pregnancy were reported,with biopsy-proven pauci-immune crescentic glomerulonephritis at postpartum.It is most rare that pauci-immune crescentic glomerulonephritis as the cause of renal failure in pregnancy.Their renal function could remain stable for some time due to timely and appropriate treatment.Therefore,the pregnant and maternal who have the performance of renal impairment should be closely tracked their blood pressure,urinary protein and renal function,if necessary,execute renal biopsy,for a clear and accurate pathological diagnosis is of great significance to grasp the opportunity of treatment.But the long-term prognosis is still poor. Here two cases of renal failure occurring in pregnancy were reported, with biopsy-proven pauci-immune crescentic glomerulonephritis at postpartum. It is most rare that pauci-immune crescentic glomerulonephritis as the cause of renal failure in pregnancy.Their renal function could remain stable for some time due to timely and appropriate treatment.Therefore, the pregnant and maternal who have the performance of renal impairment should be closely tracked their blood pressure, urinary protein and renal function, if necessary, execute renal biopsy, for a clear and accurate pathological diagnosis is of great significance to grasp the opportunity of treatment.But the long-term prognosis is still poor.
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