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本文对４１例晚期胃癌进行随机分组治疗。治疗组以羟基喜树碱为主配合中药治疗，对照组为单用中药治疗。结果显示近期有效率治疗组６３．６％，对照组３１．５％（Ｐ＜０．０５）。６个月生存率，治疗组６８．１％，对照组３６．８％（Ｐ＜０．０５）。６个月生存者体力状况，ｋａｒｎｆｓｋｙ计分≥６０分，治疗组７２．２％，对照组４２．１％（Ｐ＜０．０５）。治疗过程未见全身毒性反应。说明羟基喜树碱配合中药适合于治疗晚期胃癌。
This article randomized 41 patients with advanced gastric cancer. The treatment group was mainly treated with hydroxycamptothecin and traditional Chinese medicine, and the control group was treated with Chinese medicine alone. The results showed that the effective treatment group was 63.6% and the control group was 31.5% (P<0.05). The 6-month survival rate was 68.1% in the treatment group and 36.8% in the control group (P<0.05). Physical status of survivors at 6 months, karnfsky score ≥60 points, treatment group 72.2%, and control group 42.1% (P<0.05). No systemic toxicity was seen during the treatment. This shows that hydroxycamptothecin combined with traditional Chinese medicine is suitable for the treatment of advanced gastric cancer.