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流行性乙型脑炎的有效治疗与预防,国内外文献尚少记载,目前唯一的疗法是一般的护理与对症治疗,至于特殊疗法方面,会有人使用各种磺胺剂①—④和各种抗生素④—⑥,均无效果。亦有人试用对氨安息香酸于少数病例,亦毫无功效。Vollmer和Hurlbut氏⑦在小白鼠体内用皮质酮(cortison)作治疗试验,不但无效,而且在高温度时还可以增加其死亡率。化学药品既无疗效,于是不得不借助于血清疗法。有人用恢复期病人血清治疗①,虽谓有效,惜仅试用于一例。另有人用输血疗法⑧—⑨,亦不见功效。1952年全国流行性乙型脑炎防治工作总结报告⑩,认为应用血浆治疗,在降低病死率方面比较有效。Rivers氏⑾谓免疫血清在动物体内有保护效力。国内学者曾试制高度免疫马血清⑿,经
The effective treatment and prevention of Japanese encephalitis is not well documented at home and abroad. Currently, the only treatment is general nursing and symptomatic treatment. As for special treatment, there are people who use various sulfonamides 1-4 and various antibiotics. 4-6, no effect. Some people also tried ammonia benzoic acid in a few cases, and there was no effect. Vollmer and Hurlbut’s 7 corticosteroid treatment in mice is not only ineffective, but also increases mortality at high temperatures. Chemicals have no therapeutic effect and they have to resort to serum therapy. Some people use the serum of convalescent patients to treat 1, although it is effective, but only try for one case. Another person uses blood transfusion therapy 8-9, but also see no effect. In 1952, the national summary report on the prevention and treatment of Japanese encephalitis (JE) 10 concluded that the use of plasma therapy was effective in reducing the mortality rate. Rivers (11) states that immune serum has protective efficacy in animals. Domestic scholars have tried highly immunized horse serum (12).