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目的：探讨卡前列甲酯栓配伍丙酸睾酮的引产效果。方法：１２０例１０～１６ｗｋ孕妇随机分为２组：Ｉ组年龄（２４±ｓ４）ａ，用丙酸睾酮１００ｍｇ，ｉｍ，ｑｄ×３ｄ，以后阴道放置卡前列甲酯栓１ｍｇ，ｑ２ｈ，不超过５ｍｇ。ＩＩ组年龄（２３±４）ａ，羊膜腔内注入依沙吖啶１００ｍｇ。结果：Ｉ组和ＩＩ组引产成功率分别为８７％和８８％（Ｐ＞０．０５）。完全流产率分别为３０％和１０％，用药至胎儿娩出时间分别为１５ｈ和５７ｈ，住院时间分别为３ｄ和４ｄ，差别均有显著意义（Ｐ＜０．０５）。结论：卡前列甲酯栓配伍丙酸睾酮终止１０～１６ｗｋ妊娠，是一种有效、快速、安全的引产方法。
Objective: To investigate the induction effect of carbamazepin suppository combined with testosterone propionate. Methods: 120 cases of 10 ~ 16wk pregnant women were randomly divided into 2 groups: group I (24 ± s4) a, with testosterone propionate 100mg, im, qd × 3d, after vaginal cardinal methylester suppository 1mg, q2h, 5mg. Group II age (23 ± 4) a, amniotic cavity injection of ethacridine 100mg. Results: The success rates of induction of labor in group I and group II were 87% and 88%, respectively (P> 0.05). The rates of complete abortion were 30% and 10% respectively. The time from delivery to fetus was 15h and 57h respectively, and the length of hospital stay was 3d and 4d respectively (P <0.05). Conclusions: Cardinal methylester suppository with testosterone propionate terminates 10 ~ 16 weeks pregnancy, which is an effective, rapid and safe method of induction of labor.