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目的探讨青少年甲状腺癌患者的预后情况。方法回顾性分析16例未成年甲状腺癌患者的临床资料。结果低钙血症是主要的术后并发症,其中3例(18.8%)是暂时性的,1例是永久性的。喉返神经损伤2例。随访平均7.5年(2个月~21年),12例生存同时无肿瘤复发及转移,2例生存但有肿瘤复发或转移,1例死于肿瘤转移,1例失访。乳头状腺癌、滤泡状腺癌及髓样癌患者总的10年生存率分别为100%、100%及50%。结论18岁以下的分化型甲状腺癌患者容易发生淋巴结转移,不管分期早晚及分化类型的甲状腺癌患者均具有较好的预后。
Objective To investigate the prognosis of adolescent thyroid cancer patients. Methods Retrospective analysis of 16 cases of undetermined thyroid cancer in patients with clinical data. Results Hypocalcemia was the major postoperative complication, of which 3 (18.8%) were transient and 1 was permanent. Recurrent laryngeal nerve injury in 2 cases. The average follow-up was 7.5 years (ranged from 2 months to 21 years). No tumor recurrence and metastasis was found in 12 cases, 2 cases survived but had tumor recurrence or metastasis, 1 case died of tumor metastasis and 1 case was lost to follow-up. The 10-year overall survival rates for papillary adenocarcinoma, follicular adenocarcinoma and medullary carcinoma were 100%, 100%, and 50%, respectively. Conclusion Patients with differentiated thyroid carcinoma under 18 years of age are prone to lymph node metastasis. Patients with advanced thyroid carcinoma and differentiated thyroid cancer have a good prognosis.