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目的 :探讨老年癌症患者化疗应注意的问题。方法 :采用该领域前沿动态和最新成果以及所积累的临床经验资料。结果 :在化疗期间 ,不考虑老年癌症患者引起的生理变化如癌的浸润损伤、癌的异位内分泌、癌的血液流变学及癌的生物化学反应等特殊性 ,就会影响抗癌药物在老年人体内的代谢、吸收、排泄及骨髓对药物的耐受性。如给患者止吐、升血并配合保护心、脑、肝、肾、肺等药物的综合治疗 ,不仅消除了毒副作用 ,还保持其良好的生活质量。结论 :老年癌症患者应综合治疗才能使化疗顺利进行。
Objective: To discuss the problems that should be paid attention to in chemotherapy for elderly cancer patients. Methods : Adopt frontier dynamics and latest results in the field and accumulated clinical experience data. RESULTS: During chemotherapy, physiologic changes caused by cancer in elderly patients were not considered, such as cancer infiltration damage, cancer ectopic endocrine, cancer hemorheology, and cancer biochemical reactions, which would affect the anti-cancer drugs. Metabolism, absorption, excretion, and tolerance of the bone marrow to drugs in the elderly. Such as the patient’s antiemetic, blood rise and with the protection of the heart, brain, liver, kidney, lung and other drugs, comprehensive treatment, not only eliminates toxic side effects, but also maintain its good quality of life. Conclusion : The elderly patients with cancer should be treated comprehensively to make the chemotherapy progress smoothly.