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重症急性胰腺炎(SAP)是以胰腺坏死、出血为特征的炎症反应,常波及胰周组织及远处器官,病因复杂,病情重,并发症多,预后不良,病死率可高达20%～30%。SAP的发病机制尚未完全阐明,寻找更有效的方法阻断SAP的恶化和降低其死亡率一直是人们近年来研究的热点。1988年Rinderkenchet[1]
Severe acute pancreatitis (SAP) is an inflammatory reaction characterized by necrosis and hemorrhage of the pancreas. It frequently affects the peripancreatic tissues and distant organs. The etiology is complicated, with severe illness, multiple complications and poor prognosis. The mortality rate can reach as high as 20% ~ 30 %. The pathogenesis of SAP has not been fully elucidated. Finding a more effective method to block the deterioration of SAP and reduce its mortality has been a hot topic in recent years. 1988 Rinderkenchet [1]