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目的观察应用低分子肝素钙干预肺源性心脏病合并冠心病患者后QT离散度(QTcd)、JT离散度(JTcd)的变化。方法将145例肺源性心脏病合并冠心病患者随机分成两组,其中干预组76例,给予低分子肝素钙干预,对照组69例,给予常规治疗。观察两组治疗前后QTcd、JTcd的变化情况。结果干预组与对照组在治疗前QTcd、JTcd差异无统计学意义(P>0.05),治疗后干预组QTcd、JTcd较对照组明显改善(P<0.01)。结论低分子肝素钙对肺源性心脏病合并冠心病患者的QTcd、JTcd有显著改善作用。
Objective To observe the changes of QT dispersion and JT dispersion after intervention of low molecular weight heparin calcium in patients with coronary heart disease complicated with pulmonary heart disease. Methods 145 cases of patients with cor pulmonale complicated with coronary heart disease were randomly divided into two groups, 76 cases in the intervention group were given low molecular weight heparin calcium intervention and 69 cases in the control group were given routine treatment. The changes of QTcd and JTcd in two groups before and after treatment were observed. Results There was no significant difference in QTcd and JTcd between the intervention group and the control group before treatment (P> 0.05). After treatment, the QTcd and JTcd in the intervention group were significantly improved compared with the control group (P <0.01). Conclusions Low molecular weight heparin calcium can significantly improve QTcd and JTcd in patients with pulmonary heart disease complicated with coronary heart disease.