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目的:观察脑梗塞、脑动脉硬化患者血液流变学、血脂、脂蛋白的不同变化。方法:测定两组患者各40例血液流变学、血脂、脂蛋白含量,并与40例正常组对照。结果:两组血液流变学7项指标及血清胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、极低密度脂蛋白胆固醇与对照组相比,差异有显著性(P<0.01),脑梗塞组全血粘度、纤维蛋白原、红细胞聚集指数、血清甘油三酯与脑动脉硬化组对照,差异有显著性(P<0.01)。结论:脂质代谢紊乱是两组共同的病理基础,调整血脂代谢,对治疗脑动脉硬化,预防脑梗塞发生,有重要意义。
Objective: To observe the changes of blood rheology, blood lipid and lipoprotein in patients with cerebral infarction and cerebral arteriosclerosis. Methods: The hemorrheology, blood lipid and lipoprotein of 40 patients in two groups were measured and compared with 40 normal patients. Results: Seven indexes of hemorheology, serum cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, and very low density lipoprotein cholesterol in the two groups were significantly different from those in the control group (P <0.01) , Whole blood viscosity, fibrinogen, erythrocyte aggregation index, serum triglyceride and cerebral arteriosclerosis group in cerebral infarction group, the difference was significant (P <0.01). Conclusion: The disorder of lipid metabolism is the common pathological basis of both groups. It is of great significance to regulate blood lipid metabolism and to treat cerebral arteriosclerosis and prevent cerebral infarction.