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目的探讨老年人群中性别对颈动脉内膜中层厚度(IMT)的影响以及颈动脉IMT与心脑血管事件的相关性。方法选择老年患者147例,男71例,女76例,测量身高、体重、血压、血脂,超声检测颈动脉IMT,并进行男女各变量比较及颈动脉IMT与心肌梗死、脑卒中相关性分析。结果女性≥80岁颈动脉IMT明显高于<80岁患者(0.93 mm vs 0.80 mm,P<0.05);而男性≥80岁与<80岁颈动脉IMT比较差异无统计学意义(P>0.05);在心肌梗死的logistic回归分析中,入选的变量有性别、年龄、TC、LDL-C、HDL-C、颈动脉IMT,结果提示,男性、年龄与心肌梗死呈正相关(P=0.006,P=0.038),TC、LDL-C、HDL-C及颈动脉IMT均移出模型。而在脑卒中的影响因素分析中,最终模型只有颈动脉IMT与脑卒中呈正相关(P=0.041)。结论本研究人群的性别、年龄与心肌梗死相关,而颈动脉IMT则与脑卒中相关。
Objective To investigate the effect of gender on carotid artery intima-media thickness (IMT) in elderly population and the correlation between carotid IMT and cardiovascular and cerebrovascular events. Methods A total of 147 elderly patients, 71 males and 76 females, were selected for the study. Height, weight, blood pressure and blood lipids were measured. The carotid IMT was detected by ultrasound. The variables of male and female variables and the correlation between carotid IMT and myocardial infarction and stroke were analyzed. Results The carotid IMT was significantly higher in female than 80-year-old patients (0.93 mm vs 0.80 mm, P <0.05), while there was no significant difference in carotid IMT between male ≥80 and <80 years (P> 0.05) In the logistic regression analysis of myocardial infarction, the variables of gender, age, TC, LDL-C, HDL-C and carotid IMT were included in the logistic regression analysis. The results showed that male and age were positively correlated with myocardial infarction (P = 0.006, 0.038), TC, LDL-C, HDL-C and carotid IMT were all out of the model. In the analysis of the influencing factors of stroke, only the carotid IMT was positively correlated with stroke in the final model (P = 0.041). Conclusions The gender and age of the study population were associated with myocardial infarction, whereas carotid IMT was associated with stroke.