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作者报告一例经明确诊断的弥漫性淋巴细胞瘤的病人合并有肾病综合征和肾衰。经环磷酰胺、正定霉素、长春新碱及强的松联合治疗55天后,已无蛋白尿,肌酐清除率亦增高,4个月内恶性淋巴瘤完全缓解。继续应用维持量,有13个月的时间病人保持在缓解期,肾功能正常,亦无蛋白尿。作者指出,在患恶性肿瘤的病人中不伴有肾静脉栓塞和淀粉样变或肾肿瘤浸润的肾病综合征少见。据报告,它最常见于淋巴网细胞瘤(37例),各种癌症(28例),非淋巴网细胞性淋巴瘤(6例),白血病
The authors report that a patient diagnosed with diffuse lymphoma had nephrotic syndrome and renal failure. After cyclophosphamide, naringin, vincristine and prednisone combined treatment of 55 days, no proteinuria, creatinine clearance also increased, 4 months of complete remission of malignant lymphoma. Continue to maintain the volume, there are 13 months of patients remain in remission, normal renal function, nor proteinuria. The authors note that nephrotic syndrome, which is not associated with renal vein thrombosis and amyloidosis or renal tumor infiltration in patients with malignant tumors, is uncommon. It is reported to be most commonly found in lymphomas (n = 37), various cancers (n = 28), non-lymphocytic lymphoma (n = 6), leukemia