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目的重视肝硬化红细胞比容(HCT)过低患者测定血浆凝血酶原时间(PT)的抗凝剂用量问题。方法以HCT<25%的40例肝硬化患,用常规方法测定PT与用Macgann公式计算抗凝剂用量后所再测的PT对比。结果按照常规方法使用抗凝剂检测HCT<25%肝硬化患者的PT结果是不可靠的。结论给HCT<25%肝硬化患者测定PT时,务必先用Macgann公式计算抗凝剂用量。
Objective To address the issue of the amount of anticoagulant used to measure plasma prothrombin time (PT) in patients with cirrhosis with low hematocrit (HCT). Methods Forty cirrhotic patients with an HCT of <25% were studied by conventional methods to measure the PT and the PT measured after calculation of the amount of anticoagulant using the Macgann formula. Results The PT results of anticoagulants in patients with HCT <25% of cirrhotic patients according to conventional methods were unreliable. Conclusions For patients with HCT <25% of patients with cirrhosis, the Macgann formula must be used to calculate the amount of anticoagulant.