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近年来国内外许多学者都在探索光化学药物诊治癌瘤的方法,我院亦于1984年12月开始,试治鼻咽癌,至1986年1月底,共治疗45例,取得一定的近期临床疗效,现报告如下: 一、药物:光卟啉注射液(YHPD)是由江苏杨州生化制药厂生产提供,瓶装棕色液,每瓶含量125mg/25ml,达到避光保存和运输的要求,平时放冰箱(约3℃)保存。 二、光源:用南京七七二厂生产的氩离子激光机,泵浦北京光电研究所生产的染料激光仪,工作物质为Rodamine B、利用治疗的波长为6300,偶合光纤末端输出功率保持在300mw以上。 三、临床资料 (一)年龄性别:年龄最小20岁,最大62岁。男性33例,女性12例。 (二)病例:Ⅰ期2例:放射治疗后鼻咽局部复
In recent years, many scholars at home and abroad are exploring methods of photochemical drug diagnosis and treatment of cancer, our hospital also began in December 1984, trial treatment of nasopharyngeal carcinoma, to the end of January 1986, a total of 45 cases were treated, achieved a certain short-term clinical efficacy , The report is as follows: First, drugs: Photoperiphrone injection (YHPD) is produced by Jiangsu Yangzhou Biochemical Pharmaceutical Factory, bottled brown liquid, each bottle content 125mg/25ml, to avoid light preservation and transportation requirements, usually put Refrigerator (about 3 °C) to save. Second, the light source: using the Nanjing 718 factory argon ion laser machine, pump dye laser produced by the Beijing Institute of Optometry, the working substance is Rodamine B, the use of treatment wavelength is 6300, the end of the coupling fiber output power remains at 300mw the above. Third, clinical data (A) age and sex: youngest 20 years old, maximum 62 years old. There were 33 males and 12 females. (B) Cases: 2 cases of phase I: partial recurrence of nasopharyngeal after radiotherapy