血栓性血小板减少性紫癜(簡称TTP)是一种急性的、通常是致命性的、病因未明的综合征。国内罕见,仅报告数例。我们曾遇到一例,现报告如下。患者王×,女性,17岁。因尿呈浓茶样、巩膜黄染、四肢瘀点一周,持续鼻衄3小时,于1979年5月17日入院。体检:体温37℃。神志清楚,皮肤有散在瘀点,巩膜中度黄染。双側瞳孔等大,对光反射存在。颈软。心肺无异常。肝肋下0.5厘米可触及,脾未触及。未引出病理反射。眼底正常。化验:血红蛋白6.7克;白细胞4,950,有核红细胞2个/100个白细胞,血片见破碎红细胞、异形及多染性红细胞;血小板1万;网织红細胞7.1％。尿蛋白(±),尿胆元1:160,胆红素阳性。尿潜血试验阴性。大便潜血试验(++)。Rous试验阴性。黄疸指数15单位;范登伯 Thrombotic thrombocytopenic purpura (TTP for short) is an acute, usually fatal, etiological syndrome. Domestic rare, only reported a few cases. We have encountered one case and are reported as follows. Patient king ×, female, 17 years old. Due to urine was thick tea-like, scleral yellow dye, four limbs petechiae week, continuing epistaxis 3 hours, on May 17, 1979 admission. Physical examination: body temperature 37 ℃. Consciousness, the skin scattered petechia, sclera moderate yellow dye. Bilateral pupils and other large, there is light reflex. Neck soft. No abnormal heart and lung. 0.5 cm under the ribs can be touched, the spleen not touched. Did not lead to pathological reflex. Fundus normal. Laboratory: Hemoglobin 6.7 grams; 4,950 white blood cells, nucleated red blood cells 2/100 white blood cells, blood see see broken red blood cells, irregular and stained erythrocytes; platelets 1 million; reticulocytes 7.1%. Urinary protein (±), urinary bile 1: 160, bilirubin positive. Urinary occult blood test negative. Fecal occult blood test (++). Rous test negative. Jaundice index 15 units; Van den Berg