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目的探索急性有机磷农药中毒致迟发性神经病变的治疗方法,方法将我院7年中发生的急性有机磷农药中毒致迟发性神经病变15例进行中西结合治疗:甲基强的松龙针剂80mg静脉滴注,1天1次,连用1周逐步减量停用;维生素B1针剂每次100mg,每天1次肌注;维生素B12针剂每次500μg,每天肌注1次。连用2周;中药治疗:基本药物:一叶秋艹5g、石蒜3g、白芷5g、桃仁、红花各10～15g、当归10～15g、川芎10～15g、赤芍药10～15g、全蝎5～10g、白附子5～10g、白僵蚕10～15g、蜈蚣1～3条、钩藤10～30g、黄芪30～60g、甘草5～10g。加减:兼热加金银花30g、连翘10～30g、板蓝根10～30g,每日1剂,水煎服,连用2周;理疗、针灸、按摩。2周为1疗程,并进行疗效分析。结果10例2个疗程后症状基本消失,4例经5个疗程痊愈,1例经5个疗程治疗后留有双下肢轻瘫,但生活能自理。结论中西结合治疗急性有机磷农药中毒致迟发性神经病变效果好,值得推广。
Objective To explore the treatment of delayed neuropathies induced by acute organophosphorus pesticide poisoning.Methods 15 cases of delayed neuropathies caused by acute organophosphorus pesticide poisoning in our hospital for 7 years were treated with Chinese and western medicines: methylprednisolone Inject 80mg intravenous injection, 1 day 1 times, once a week with a gradual reduction of deactivation; vitamin B1 injection every 100mg, 1 intramuscular injection daily; vitamin B12 injection 500μg each time intramuscular injection 1 times. Once every two weeks; Chinese medicine treatment: basic drugs: a leaf autumn 艹 5g, Lycium 3g, Angelica 5g, peach, saffron 10 ~ 15g, angelica 10 ~ 15g, Chuanxiong 10 ~ 15g, 5 ~ 10g, white aconite 5 ~ 10g, white silkworm 10 ~ 15g, centipedes 1 to 3, Uncaria 10 ~ 30g, Astragalus 30 ~ 60g, licorice 5 ~ 10g. Addition and subtraction: And hot plus honeysuckle 30g, forsythia 10 ~ 30g, Radix 10 ~ 30g, daily 1, Shuijianbi, once every 2 weeks; physiotherapy, acupuncture and massage. 2 weeks for a course of treatment, and efficacy analysis. Results After 10 courses of 2 courses, the symptoms disappeared, 4 cases recovered after 5 courses, and 1 patient had bilateral lower extremity paresis after 5 courses of treatment, but life could take care of themselves. Conclusion The combination of Chinese and western treatment of acute organophosphorus pesticide poisoning caused by delayed neuropathic effect is good, it is worth promoting.