《药物中间体化学(第2版)》在第1版的基础上,以中间体为主线,在加强理论知识的同时,详细介绍了包括药物中间体合成设计、环合反应、硝化反应、磺化反应、酰化反应、加成反应、氧化反应、还原反应、缩合反应、氨解反应、烷基化反应、卤化反应、手性药物中间体合成以及药物中间体的分离与结构鉴定等内容,并重点介绍了化合物的新型合成方法与检测手 Based on the first edition, based on the first edition, “Intermediates of Pharmaceutical Intermediate (Second Edition)” focuses on the intermediates. While strengthening the theoretical knowledge, this paper introduces the synthesis and design of drug intermediates, cyclization reaction, nitration reaction, Chemical reaction, acylation reaction, addition reaction, oxidation reaction, reduction reaction, condensation reaction, ammonolysis reaction, alkylation reaction, halogenation reaction, synthesis of chiral drug intermediates and separation and structural identification of pharmaceutical intermediates, The new synthetic methods and testing methods of the compounds are also introduced