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目的探讨格列美脲与甘精胰岛素联合用药治疗2型糖尿病的疗效。方法从2013年6月至2014年6月我院收治的2型糖尿病患者中随机性抽取40例作为研究对象,40例患者均给予格列美脲与甘精胰岛素联合用药治疗,对于患者空腹血糖、餐后2h血糖、糖化红蛋白、低血糖以及体重指标。结果患者治疗后空腹血糖、餐后2h血糖、低血糖以均有明显下降,与治疗前比较,数据差异具有统计学意义(P<0.05);治疗前后体重指标比较,无明显差异(P>0.05)。结论格列美脲与甘精胰岛素联合用药治疗2型糖尿病疗效显著,可以有效改善患者空腹血糖、餐后2h血糖、低血糖指标,是一种安全有效的治疗方法,值得临床推广和应用。
Objective To investigate the efficacy of glimepiride and insulin glargine in the treatment of type 2 diabetes mellitus. Methods From June 2013 to June 2014, 40 patients with type 2 diabetes mellitus admitted to our hospital were selected randomly as the research object. Forty patients were given glimepiride combined with insulin glargine for the treatment of patients with fasting blood glucose , 2h postprandial blood glucose, glycosylated hemoglobin, hypoglycemia and body mass index. Results After treatment, fasting blood glucose, postprandial blood glucose and hypoglycemia were significantly decreased at 2h after treatment. There were significant differences between before and after treatment (P <0.05), before and after treatment, there was no significant difference in body mass index (P> 0.05 ). Conclusion The combination of glimepiride and insulin glargine treatment of type 2 diabetes significant effect, can effectively improve the patients fasting blood glucose, 2h postprandial blood glucose, hypoglycemia, is a safe and effective treatment, worthy of clinical promotion and application.