论文部分内容阅读
本研究采用外周血淋巴细胞SCE 和MN 两项指标,对铝作业工人中的电解工和碳素工进行了细胞遗传学监测。结果表明,电解工和碳素工的SCE 频率分别为7.32和6.91SCE s/cell,显著高于对照组(5.73SCEs/cell,P<0.01,且电解与碳素工人间的SCE 频率也有显著性差异(P<0.05)。电解和碳素工人的微核细胞率分别为1.03‰和0.80‰,均显著高于对照(0.15‰),这些表明铝作业工人的细胞遗传物质受到了损伤,并且电解工受损程度高于碳素工。经用MMC 诱发后,碳素工人的诱发SCE频率(21.88SCE s/cell)与对照组(21.52SCE s/cell)比无显著性差异,而电解工的诱发SCE 频率(25.24SCE s/cell)与对照比仍有显著性差异(P<0.01),表明电解工的DNA 损伤修复系统功能有所降低。
In this study, peripheral blood lymphocytes SCE and MN two indicators, aluminum workers in electrolytic and carbon workers carried out cytogenetic monitoring. The results showed that the SCE frequencies of electrolytes and carbon workers were 7.32 and 6.91 SCE / cell, respectively, which were significantly higher than that of the control group (5.73 SCE / cell, P <0.01) (P <0.05). The rates of micronuclei in electrolytes and carbon workers were 1.03 ‰ and 0.80 ‰, respectively, which were significantly higher than those in the control (0.15 ‰), which indicated that the cytogenetic substances of aluminum workers were damaged, and the electrolysis The damage degree of workers was higher than that of carbon workers.The carbon-induced SCE frequency (21.88SCE s / cell) was not significantly different from that of control group (21.52SCE s / cell) The frequency of induced SCE (25.24 SCE s / cell) was still significantly different from that of the control (P <0.01), indicating that the function of DNA repair system in electrolytes was reduced.