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目的 探讨~(18)F-FDG和~(99m)Tc-MIBI两种显像方法对肺癌诊断价值。方法 患者禁食4小时以上,静脉注入37MBq~(18)F-FDG,静卧45分钟后进行FDG显像。MIBI显像方法是早餐吃油煎鸡蛋喝牛奶,静脉注入1.11GBq~(99m)Tc-MIBI,之后60分钟进行胸部断层显像检查,32例肺癌患者加作120分钟延迟显像。结果 41例FDG显像的阳性率是92.7％(38/41),靶本比2.90±1.35。41例MIBI 60分钟显像的阳性率是75.6％(31/41),靶本比1.92±0.59;32例延迟显像的阳性率为78.1％(25/32),靶本比1.78±0.53。FDG的靶本比和阳性率高于MIBI(P<0.05),鳞癌和腺癌FDG显像的靶本比无差异(P>0.05)。结论 FDG的显像质量和阳性率均优于MIBI,MIBI阴性显像结果是否与多药耐药有关有待进一步研究。
Objective To investigate the diagnostic value of ~ (18) F-FDG and ~ (99m) Tc-MIBI imaging in lung cancer. Methods Patients were fasted for more than 4 hours. Intravenous injection of 37MBq ~ (18) F-FDG and FDG imaging were performed 45 minutes after lying still. MIBI imaging method is to eat fried eggs for breakfast, milk, intravenous injection of 1.11GBq ~ (99m) Tc-MIBI, 60 minutes after the chest imaging examination, 32 patients with lung cancer plus 120 minutes delayed imaging. Results The positive rate of 41 cases of FDG imaging was 92.7% (38/41), and the ratio of the target to the imaging was 2.90 ± 1.35. The positive rate of imaging in 61 cases of MIBI at 60 minutes was 75.6% (31/41) and the ratio of the target was 1.92 ± 0.59 ; 32 cases of delayed imaging positive rate was 78.1% (25/32), the target ratio of 1.78 ± 0.53. The ratio of the target and the positive rate of FDG was higher than that of MIBI (P <0.05). There was no significant difference in the FDG imaging between squamous cell carcinoma and adenocarcinoma (P> 0.05). Conclusion FDG imaging quality and positive rate are better than MIBI, MIBI negative imaging results related to multidrug resistance remains to be further studied.