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目的探讨Graves病与特发性血小板减少性紫癜(ITP)的关系。方法回顾分析了16例Graves病合并ITP患者的诊断及治疗情况。结果经他巴唑或丙基硫氧嘧啶治疗甲亢症状很快控制,ITP用肾上腺皮质激素治疗者,血小板很快上升,7例口服氨肽素、参芪片一般治疗者血小板也逐渐上升。共6例于2～3年甲亢复发,其中5例再次出现血小板减少,甲亢治疗同前,针对血小板减少,口服氨肽素、参芪片一般治疗,甲亢控制,血小板也渐恢复。结论Graves病与ITP均为自身免疫疾病,在治疗方面应以控制甲亢为主,随着甲亢的好转,血小板可以恢复正常,对于血小板严重减少或出血明显者,再加用肾上腺皮质激素治疗,这样避免了不必要应用的激素给机体带来的副作用。
Objective To investigate the relationship between Graves’ disease and idiopathic thrombocytopenic purpura (ITP). Methods The diagnosis and treatment of 16 cases of Graves’ disease complicated with ITP were retrospectively analyzed. Results The treatment of hyperthyroidism by methimazole or propylthiouracil quickly controlled the symptoms, ITP with adrenal cortex hormone treatment, platelets increased rapidly, 7 cases of oral aminobislintin, Shenqi tablets general treatment of platelets also increased gradually. A total of 6 cases of hyperthyroidism recurrence in 2 to 3 years, of which 5 cases of thrombocytopenia, hyperthyroidism treated with the former, for thrombocytopenia, oral aminopeptin, Shenqi tablets general treatment, hyperthyroidism control, platelets also gradually recovered. Conclusions Both Graves’ disease and ITP are autoimmune diseases. Hyperthyroidism should be the mainstay of treatment. With the improvement of hyperthyroidism, platelets can return to normal. For patients with severe thrombocytopenia or severe bleeding, combined with adrenocorticotropic hormone therapy, Avoid unnecessary side effects of hormones to the body.