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Objective To study the chemical constituents of Bombycis Feculae.Methods Chemical constituents were isolated by HPLC-ELSD.The structures of the isolated compounds were determined by spectral means.Results Two compounds were isolated and identified as 1-deoxynojirimycin(1)and(2R,3R,5R)-2-(hydroxymethyl) piperidine-3,5-diol,named as 1,3-dideoxygalatonojirimycin(2).Conclusion Compound 2 is a new alkaloid.The extract of Bombycis Feculae,compound 1 and compound 2 show inhibitory activities againstα-glucosidase.
Objective To study the chemical constituents of Bombycis Feculae. Methods Chemical constituents were isolated by HPLC-ELSD.The structures of the isolated compounds were determined by spectral means. Results two compounds were isolated and identified as 1-deoxynojirimycin (1) and (2R, 3R, 5R) -2- (hydroxymethyl) piperidine-3,5-diol, named as 1,3-dideoxygalatonojirimycin (2) .Conclusion Compound 2 is a new alkaloid.The extract of Bombycis Feculae, compound 1 and compound 2 showhibitory activities againstα-glucosidase.