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本文应用免疫组化Ｓ－Ｐ法，探讨６３例胃癌手术标本中Ｐ（１６）／ＣＤＫ４１的表达及预后意义，结果显示ＣＤＫ４１强表达者与低表达、阴性者５年生存率差异有显著性意义（Ｐ＜０．０５），说明Ｐ（１６）／ＣＤＫ４１的表达与胃癌预后密切相关。
In this study, immunohistochemical S-P method was used to investigate the expression and prognostic significance of P(16)/CDK41 in 63 surgical specimens of gastric cancer. The results showed that there was a significant difference in 5-year survival rate between strong CDK41 expression and low expression and negative. (P<0.05), indicating that P(16)/CDK41 expression is closely related to the prognosis of gastric cancer.