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目的 :了解糖尿病患者的血糖控制及大血管并发症发生情况,并对大血管并发症相关的危险因素进行分析。方法:收集本院门诊498例糖尿病患者的临床表现、实验室检查、治疗方案及并发症发生情况,并按有无大血管并发症分组比较。采用Logistic回归分析大血管并发症相关危险因素。结果:有大血管并发症组为69例(13.9%)年龄、腰围和有高血压病史比例均显著高于无大血管并发症组(均P<0.05),而血糖控制情况、文化程度则不及无大血管并发症组(均P<0.05)。对近3年新发大血管疾病的危险因素分析显示,糖尿病患者腰围和既往有高血压病史是其心脑血管疾病发生的危险因素,其比值比(OR)和95%可信区间(CI)分别为1.04(1.01~1.07)和2.09(1.10~3.97)。结论:门诊糖尿病患者大血管并发症发生率较高,为了有效预防并控制2型糖尿病患者的大血管并发症,加强血压控制、采取有效措施降低患者的腰围显得非常必要。
Objective: To understand the glycemic control and macrovascular complications in patients with diabetes mellitus, and to analyze the risk factors associated with macrovascular complications. Methods: The clinical manifestations, laboratory tests, treatment options and complications of 498 diabetic patients in our hospital were collected and compared by grouping with or without major vascular complications. Logistic regression analysis of risk factors associated with macrovascular complications. Results: There were 69 cases (13.9%) of patients with macrovascular complications in the age, waist circumference and history of hypertension were significantly higher than those without macrovascular complications (all P <0.05), while the blood glucose control, educational level is less than No macrovascular complications (all P <0.05). Analysis of risk factors for newly diagnosed macrovascular disease in recent 3 years showed that waist circumference and previous history of hypertension were the risk factors of cardiovascular and cerebrovascular diseases in patients with diabetes mellitus. The odds ratio (OR) and 95% confidence interval (CI) Respectively 1.04 (1.01-1.07) and 2.09 (1.10-3.97). Conclusion: The incidence of macrovascular complications is high in outpatients with diabetes mellitus. In order to effectively prevent and control the macrovascular complications in type 2 diabetic patients and to strengthen the blood pressure control, it is necessary to take effective measures to reduce the waist circumference of patients.