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目的：观察四川叶下珠的抗乙型肝炎病毒（ＨＢＶ）作用。方法：ＨｅｐＧ２．２．１５细胞培养３６小时后，再用含不同浓度叶下珠的培养液培养４８小时，测定培养上清液中的 ＨＢｅＡｇ含量。结果：四川叶下珠可有效地抑制 ＨｅｐＧ２．２．１５细胞ＨＢｅＡｇ的表达，其中１００、１５０μｇ／ｍｌ两个浓度组的作用最强。结论：四川叶下珠具有一定的抗ＨＢＶ作用。
Objective: To observe the anti-hepatitis B virus (HBV) effect of Sichuan Yexiazhu. METHODS: HepG2.2.15 cells were cultured for 36 hours, then cultured in different concentrations of the lower bead culture medium for 48 hours, and the HBeAg content in the culture supernatant was measured. RESULTS: Sichuan Xiazhuzhu could effectively inhibit the expression of HBeAg in HepG2.2.15 cells, of which the two concentrations of 100 and 150 μg/ml had the strongest effect. Conclusion: Sichuan leaf under the pearl has a certain anti-HBV effect.