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目的探讨严重急性呼吸道综合征(SARS)患者在病程中肝功能的变化规律,以进一步认识SARS的临床特征。方法以在太原市5大医院住院治疗的170例SARS患者为研究对象,定期检查肝功能。结果多数患者转氨酶[包括丙氨酸转氨酶(ALT)和天冬氨酸转氨酶(AST)]在疾病的第9天62.5%患者ALT升高,所有患者血清总蛋白始终正常,而40%～72%的患者血清白蛋白降低。结论SARS患者病程中可出现肝功能的异常,防治中应予以注意。
Objective To investigate the changes of liver function in patients with severe acute respiratory syndrome (SARS) during the course of the disease so as to further understand the clinical features of SARS. Methods A total of 170 SARS patients hospitalized in the five major hospitals in Taiyuan City were studied. Liver function was checked regularly. Results In most patients, ALT and AST were increased in 62.5% of patients on the 9th day of disease. Total serum protein was always normal in all patients, and 40% -72% Of patients with serum albumin decreased. Conclusion There may be abnormal liver function in the course of SARS patients, which should be paid attention to in prevention and treatment.