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哺乳动物雷帕霉素靶蛋白(mTOR)是一种非典型丝氨酸/苏氨酸蛋白激酶,属于磷脂酰肌醇3-激酶相关激酶蛋白家族,参与体内多条信号通路,影响转录及蛋白质合成,在细胞的增殖、生长、分化过程中起着中心调控作用。胰高血糖素样肽-1(GLP-1)是肠道L细胞分泌的一种具有葡萄糖依赖性促胰岛素分泌功能的肠促胰岛素,与其受体相结合可激活相应偶联的信号传导通路,产生促进胰岛β细胞增殖与分化、改善心肌功能、营养及保护神经等生理学效应,且部分效应可
Mammalian target of rapamycin (mTOR) is an atypical serine / threonine protein kinase, belonging to phosphatidylinositol 3-kinase-related kinase protein family, involved in multiple signal pathways in the body, affecting transcription and protein synthesis, In the cell proliferation, growth, differentiation plays a central role in regulation. Glucagon-like peptide-1 (GLP-1), an insulin-secreting insulin-secreting insulin secretin secreted by intestinal L cells, activates the corresponding coupled signal transduction pathway in combination with its receptor, Resulting in the promotion of pancreatic β-cell proliferation and differentiation, improve myocardial function, nutrition and neuroprotection and other physiological effects, and some effects may