复方枸橼酸钠注射液,是医院临床常用的抗凝血药。其中枸橼酸钠的含量测定,多采用以橙黄Ⅳ为指示剂的酸量法、或离子交换法。酸量法操作简单,但终点不明显、不易掌握;离子交换法结果准确,但操作较麻烦。作者根据混合指示剂具有变色范围窄的优点’“,,选用橙黄IV—亚甲兰混合指示剂滴定,不但操作方法简单,而且终点变色明显, Compound sodium citrate injection, is commonly used in hospital clinical anticoagulant. Which sodium citrate content determination, the more use of orange yellow Ⅳ as the indicator of acid, or ion exchange method. Acid method is simple, but the end is not obvious, not easy to grasp; ion exchange method results are accurate, but the operation is more troublesome. The author according to the mixed indicator has the advantages of a narrow range of discoloration ’,, ,, use orange yellow IV-methylene blue mixed indicator titration, not only the operation method is simple, and the end discoloration significantly,