皮肌炎是一种急性或慢性的皮肤和肌肉的炎症性疾病。由于其病因和发病机制尚不十分明了,目前尚无有效的治疗方法。我院于1998年5月应用蝮蛇抗栓酶-3治疗1例,收到满意的效果,现报告如下。1 病例摘要 患者女性,30岁,农民。1998年5月21日以全身无力伴心慌半年,近1个月加重收住入院。患者7个月前因受凉而出现咳嗽、咳痰、胸痛,当时诊断为肺炎,应用青霉素、链霉素等药治疗好转。自此自觉全身乏力,以四肢为重,肌肉疼痛,并有压痛。2个月后上肢肌无力,上举困难不能梳头,下肢抬腿困难,只能慢步行走十几米。眼睑部出现红色斑片,4个月后出现说话声音嘶哑,并自诉心慌,曾到外地诊断皮肌炎治疗效果欠佳。近1个月来上述症状加重,出现吞咽困难,大 Dermatomyositis is an acute or chronic inflammatory disease of the skin and muscles. Because of its etiology and pathogenesis is not yet clear, there is no effective treatment. Our hospital in May 1998 the application of viper antithrombin -3 treatment in 1 case, received satisfactory results, are as follows. 1 Case Summary Female patient, 30 years old, farmer. On May 21, 1998, he was flustered with the general weakness for half a year and admitted to the hospital in the recent 1 month. Patients with cough, sputum, chest pain due to cold 7 months ago, was diagnosed with pneumonia, application of penicillin, streptomycin and other drug treatment improved. Since then consciously weak, to limbs, muscle pain, and tenderness. 2 months after the upper limb muscle weakness, on the move can not be combed hair, leg difficulties, can walk only walk more than ten meters. Eyelid appeared red patches, appearing hoarseness after 4 months, and private prosecution palpitation, had to the field diagnosis of dermatomyositis treatment ineffective. Almost a month to the above symptoms, dysphagia, large