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目的分析宁波地区2例发热伴血小板减少综合征(SFTS)患者的临床特征及流行病学资料,以期加深对该病诊治的认识。方法回顾性分析2012年5月宁波地区首发的2例SFTS的临床资料,采用统一的诊断标准和流行病学个案调查表对病例进行调查。结果 1例危重型死亡,1例普通型治愈;临床表现起病急,持续高热,全身肌痛,浅表淋巴结肿大,白细胞及血小板进行性下降;2例患者均为居住在丘陵地区老年人,有田间或草丛活动史及蜱叮咬史,患者的密切接触者均无发病病例。结论 SFTS临床表现复杂,伴有多器官损害,其死因可能与休克、病毒心肌炎、呼吸衰竭等多脏器功能衰竭有关;患者均居住在丘陵地区,有田间或草丛活动史及蜱叮咬史。
Objective To analyze the clinical characteristics and epidemiological data of 2 patients with fever and thrombocytopenia syndrome (SFTS) in Ningbo in order to deepen their understanding of the diagnosis and treatment of this disease. Methods The clinical data of two cases of SFTS, which originated in Ningbo area in May 2012, were retrospectively analyzed. The cases were investigated by using uniform diagnostic criteria and epidemiological questionnaires. Results One patient died of critical illness and one patient was cured of common type. The clinical manifestations were acute onset, persistent fever, generalized muscular dysfunction, superficial lymph nodes, progressive decrease of white blood cells and platelets. Both of the two patients were elderly living in hilly areas , There is a history of field or grass activity and history of tick bites, and no close cases of patients were found. Conclusions The clinical manifestations of SFTS are complicated with multiple organ damage. The cause of death may be related to multiple organ failure such as shock, viral myocarditis and respiratory failure. All patients live in the hilly area with history of activity or tick bites.