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肝衰竭病情重、进展快、病死率甚高,在肝衰竭发生前期进行早期预警,早期干预,对改善患者预后至关重要。目前关于肝衰竭前期的诊断标准尚不统一,关于肝衰竭前期的研究主要集中在乙型肝炎相关肝衰竭人群中进行,现就目前肝衰竭前期早期诊断、预警及治疗展开讨论。“,”Liver failure is a rapidly progressive severe condition with very high mortality rate. Therefore, early warning and early intervention in the early stage of liver failure are essential to improve the prognosis of patients. Presently, the diagnostic criteria for pre-hepatic failure are not uniform and the studies are mainly focused on people with hepatitis B-related liver failure. This article discusses the current early diagnosis, warning, and treatment of pre-hepatic failure.