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本文报道抗氰药物高铁血红蛋白(MetHb)形成剂对-氨基苯丙酮(P-aminopropiopheaone,PAPP)及其代谢产物对-羟氨苯丙酮(P-hydroxylaminopropiophenone,PHAPP)的药代动力学和药效学的量效关系。
This paper reports the pharmacokinetics and pharmacodynamics of P-aminopropiopheone (PAPP) and its metabolite P-hydroxylaminopropiophenone (PHAPP), a biosorbent drug methemoglobin (MetHb) The dose-effect relationship.