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目的:探讨舒张性心衰(DHF)患者血清三碘甲状腺原氨酸(T3)与脑利钠肽(BNP)的关系。方法:96例慢性舒张性心力衰竭患者测定血清T3和BNP浓度。其中低T3血症的舒张性心衰患者45例(低T3组),血清T3水平正常的舒张性心衰患者51例(正常T3组),观察两组BNP水平。结果:低T3组与正常T3组的舒张性心衰患者血清BNP水平均高于正常,两组分别为(557.4±92.4)ng/L和(308.9±84.6)ng/L,低T3血症组的BNP水平显著升高(P<0.01)。结论:舒张性心衰伴低T3血症患者,血清BNP升高更明显。
Objective: To investigate the relationship between serum triiodothyronine (T3) and brain natriuretic peptide (BNP) in patients with diastolic heart failure (DHF). Methods: Serum T3 and BNP concentrations were measured in 96 patients with chronic diastolic heart failure. Among them, 45 patients with T2D-induced diastolic heart failure (low T3 group) and 51 patients with normal serum T3-diastolic heart failure (normal T3 group), BNP levels were observed in both groups. Results: Serum BNP levels in patients with diastolic heart failure were significantly higher than those in patients with low T3 and normal T3 (557.4 ± 92.4 ng / L and 308.9 ± 84.6 ng / L, respectively. BNP levels were significantly increased (P <0.01). Conclusion: Patients with diastolic heart failure and hypothyroidism have higher serum BNP levels.