摘要目的研究心脏附近肺微波消融位置不引起心脏组织损伤或明显心律失常的最短距离。材料与方法该研究经机构动物保护和使用委员会批准。在CT透视引导下对12只猪模型进行微波消融。天线方向和位置被随机分配到相对平行(180°±20°)或垂直(90°±20°)于心脏表面和距离心脏0~10 mm的位置。在65 W时消融5 min或直到发生显著的心律失常(心搏停止、心脏传导阻滞、心动过缓、室上性或室性心动过速)为止。用活体染色和组织学检查评价心脏组织。用 Abstract Objective To study the shortest distance between the location of pulmonary microwave ablation in the vicinity of the heart without causing cardiac tissue damage or obvious arrhythmia. Materials and Methods The study was approved by the Institution Animal Protection and Use Committee. Guided by CT fluoroscopy, 12 pigs were subjected to microwave ablation. Antenna orientation and location were randomly assigned to be relatively parallel (180 ° ± 20 °) or vertical (90 ° ± 20 °) to the heart surface and 0 to 10 mm from the heart. Ablation was performed for 5 min at 65 W or until significant arrhythmia (asystole, heart block, bradycardia, supraventricular or ventricular tachycardia) occurred. Cardiac tissue was evaluated by in vivo staining and histology. use