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目的 :了解血安定用于婴幼儿急腹症 ,在麻醉及围术期输液 ,扩充患儿有效血容量、改善微循环等抗休克效果。方法 :选择 3 0例婴幼儿急腹症伴早期低血容性休克 ,需紧急施行“剖腹探查”手术病例 ,麻醉及围术期使用血安定输液 ,同时连续监测心率 (HR)、收缩压 (SBP)、脉压差、中心静脉压 (CVP)、血氧饱合度 (SpO2 )、手指甲床充盈时间、尿量等。结果 :使用血安定静脉输液 15min后 ,SBP回升 ,脉压差增宽 ,SpO2 升高 ,HR减慢 ,手指甲床充盈时间缩短 ,尿量增多 (P<0 .0 5 ) ;3 0min后CVP也升至正常 (P <0 .0 1) ,而且随后各时间段七项指标皆维持平稳向好的趋势。结论 :麻醉及围术期输注血安定 ,能迅速纠正急腹症伴早期低血容量性休克患儿的有效血容量不足 ,改善微循环 ,维持血流动力学稳定 ,为进一步治疗和促进患儿术后恢复创造良好条件。
OBJECTIVE: To understand the effect of diazepam on infant acute abdomen, infusion during anesthesia and perioperative period, expansion of effective blood volume in children and improvement of anti-shock effects such as microcirculation. Methods: 30 cases of infantile acute abdomen accompanied with early hypovolemic shock were selected. Emergency operation of laparotomy was performed. Anesthesia and perioperative administration of diazepam were given. Continuous monitoring of heart rate (HR), systolic pressure SBP), pulse pressure, central venous pressure (CVP), oxygen saturation (SpO2), fingernail bed filling time, urine output and so on. Results: After 15 min of intravenous blood injection, SBP increased, pulse pressure increased, SpO2 increased, HR decreased, filling time of fingernail bed decreased and urine output increased (P <0.05). After 30 min CVP Also rose to normal (P <0. 01), and then the seven indicators in each time period to maintain a stable and good trend. CONCLUSION: Anesthesia and perioperative blood transfusion can quickly correct the insufficient hypovolemia in children with acute abdomen hypovolemic shock, improve microcirculation and maintain hemodynamic stability, so as to further treat and promote Postoperative recovery to create good conditions.