目前,口服降糖药物中最常用的仍是磺酰脲类药物,其次是双胍类药物。1978年来由于发现双胍类药物可能导致乳酸性酸中毒,因而严格限制其适应症与用量。最近临床上,又试用另一类口服降糖药物,即糖甙水解酶抑制剂(glycosidhydrolase inhibitor),其中常用的是Acarbose口服降糖药物的使用,当前出现两种偏向:一是滥用。据西德人口普查中,2％服用磺酰脲类药物,而 At present, the most commonly used oral hypoglycemic agents are still sulfonylureas, followed by biguanides. Since 1978, the discovery of biguanide drugs may lead to lactic acidosis, which severely limits their indications and dosage. Recently, another type of oral hypoglycemic drug, namely glycosidhydrolase inhibitor, has been tried in clinic. Among them, the commonly used is the use of oral hypoglycemic drugs by Acarbose. There are two biases presently observed: one is abuse. According to the West Germany Census, 2% take sulfonylureas, whereas