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目的了解肠道病毒在非手足口病幼儿中的感染情况,为预防控制手足口病在儿童中的流行提供依据。方法采用实时荧光定量PCR方法,对50例≤3岁儿童的肛拭子标本共50份进行肠道病毒、肠道病毒71型(EV71)和柯萨奇病毒A16型(CoxA16)核酸检测。结果共检出17份肠道病毒核酸阳性,阳性率为34%,均为其他肠道病毒。结论健康儿童中存在其他肠道病毒的隐性感染。开展手足口病流行病学和病原学研究,将有助于提出更好的预防和控制措施。
Objective To understand the infection of enterovirus in non-hand-foot-mouth disease in infants and to provide basis for the prevention and control of hand-foot-mouth disease in children. Methods Fifty samples of 50 swabs from children ≤ 3 years old were tested for EV71 and CoxA16 by real-time PCR. Results A total of 17 positive samples of enterovirus nucleic acid were detected, the positive rate was 34%, all of which were other enteroviruses. Conclusion There are latent infections of other enteroviruses in healthy children. Developing HFD epidemiology and etiology will help to propose better prevention and control measures.