在临床抗感染选择药物中,β-内酰胺类抗生素以其毒性低、显效强的特点始终占有优势地位,过敏问题随着产品质量的提高及临床检测手段的不断完善亦得到了相应的控制。但近年来,细菌对该类抗生素的耐药性日益严重,特别是对青霉素和氨苄西林等临床常用抗生素,据报道常见致病菌对氨 Among the clinical anti-infectives, β-lactam antibiotics always hold the dominant position due to its low toxicity and markedly effective. Allergy problems are also controlled with the improvement of product quality and the continuous improvement of clinical testing methods. However, in recent years, bacterial resistance to such antibiotics is increasingly serious, especially for penicillin and ampicillin and other commonly used antibiotics, it is reported that common pathogens ammonia