动脉粥样硬化为一多因素性疾病,慢性炎症介导其发生、发展的全程。炎性反应可由血管内皮对慢性感染、氧化低密度脂蛋白或其他因素的反应引起。机体炎症反应时释放的生物活性因子,不但可预示血管事件发生的危险性,而且还参与动脉粥样硬化相关疾病的发病过程。炎症过程中具有标志性的因子已成为评价动脉粥样硬化稳定程度的具有预后意义的主要指标。 Atherosclerosis as a multifactorial disease, chronic inflammation mediated its occurrence and development of the entire process. Inflammatory reactions can be caused by the reaction of the vascular endothelium to chronic infection, oxidized low-density lipoprotein, or other factors. The body’s inflammatory response to the release of bioactive factors, not only can predict the risk of vascular events, but also involved in the pathogenesis of atherosclerosis-related diseases. A hallmark of the inflammatory process has become a major indicator of the prognostic significance of atherosclerotic stability.