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目的探讨肝外胆管类癌的临床特征和临床诊治。方法报告2例胆总管类癌并结合文献报道30例;对32例肝外胆管类癌进行分析。结果肝外胆管类癌临床少见,32例中女性23例,男性9例,发病年龄平均为49岁(19～79)岁。临床表现梗阻黄疸最为常见,占55%。肿瘤局限于胆管内为71%,诊断时己有远处转移的为29%,其肿瘤局限于胆管内病例3年存活率为100%。结论肝外胆管类癌与胆管腺癌不同,其发病年龄年轻(平均为49岁),并好发于女性。肿瘤的局部浸润为主,很少发生远处转移,根治切除后可获长期生存,对胆管类癌应行积极的根治切除。
Objective To investigate the clinical features and clinical diagnosis and treatment of extrahepatic bile duct carcinoid. Methods Two cases of cholangiocarcinoma were reported and 30 cases were reported in the literature. Thirty-two cases of extrahepatic cholangiocarcinoma were analyzed. Results Extrahepatic bile duct carcinoid was rare, of which 23 were female and 23 were male. The average age of onset was 49 years (19-79 years). Clinical manifestations of obstruction jaundice most common, accounting for 55%. The tumor was limited to 71% in the bile duct, 29% had distant metastases at diagnosis, and had a 3-year survival of 100% for biliary tumors. Conclusions Extrahepatic bile duct carcinoids, unlike bile duct adenocarcinomas, have a younger age of onset (mean, 49 years) and predominantly in women. Tumor local infiltration, rarely distant metastasis, after radical resection can be long-term survival, bile duct cancer should be performed radical radical resection.