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在小儿,特发性血小板减少性紫癜(ITP)急性型占85～95%,间歇性或慢性型占10～15%。少数慢性型患者很难治。作者对一例难治性患儿试用静脉注射免疫球蛋白制剂(Ig-SRK),以期用大剂量多价完整的 IgG 影响异常的免疫反应或减少血小板的耗损。由于这一治疗获得显著疗效,作者继续采用大剂量 Ig-SRK 治疗7例慢性或间歇性 ITP 和6例急性 ITP 患儿。
In children, idiopathic thrombocytopenic purpura (ITP) acute type accounted for 85 to 95%, intermittent or chronic type accounted for 10 to 15%. A small number of patients with chronic type is difficult to rule. The authors tested intravenous immunoglobulin preparations (Ig-SRK) in a refractory infantile in order to influence abnormal immune responses or reduce platelet depletion using high-dose, multi-valent, intact IgG. Due to the significant effect of this treatment, the authors continued to use high-dose Ig-SRK in 7 patients with chronic or intermittent ITP and 6 with acute ITP.