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目的:探讨肺炎支原体感染患儿血清中IL-8和TNF-α的变化情况。方法:回顾性分析2011年1月～2012年9月于吉林大学第二医院住院的具有完整资料的肺炎支原体肺炎患儿60例,采用ELISA检测患儿血清中IL-8和TNF-α的水平,并与60例健康儿童的检测结果进行分析比较。结果:观察组患儿血清IL-8和TNF-α的水平显著高于对照组,差异有统计学意义(P<0.05)。结论:IL-8和TNF-α能反应肺炎支原体感染的严重程度,可作为诊断和治疗的参考指标。
Objective: To investigate the changes of serum IL-8 and TNF-α in children with Mycoplasma pneumoniae infection. Methods: Sixty children with pneumonia mycoplasma pneumonia who were hospitalized in the Second Hospital of Jilin University from January 2011 to September 2012 were retrospectively analyzed. The serum levels of IL-8 and TNF-α , And compared with 60 healthy children’s test results. Results: The levels of IL-8 and TNF-α in the observation group were significantly higher than those in the control group (P <0.05). Conclusion: IL-8 and TNF-α can reflect the severity of Mycoplasma pneumoniae infection, which can be used as a reference for diagnosis and treatment.