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目的探讨早期碱剩余对感染性休克患者病情严重程度的预测价值。方法对2009年2月-2011年2月资料完整入院的感染性休克患者60例进行回顾性分析,按死亡及存活进行分组,对最初24 h的碱剩余值差异及血乳酸清除率情况进行对照研究。结果死亡组碱剩余值变化及乳酸清除率低于存活组(P<0.05)。治疗后碱剩余≤6 mmol/L较碱剩余>6 mmol/L的患者病死率明显增加,尤其是治疗后24 h碱剩余仍≤6 mmol/L病死率高达92.23%。结论早期碱剩余有助于感染性休克预后评估和指导临床治疗。
Objective To investigate the predictive value of early alkaline surplus in the severity of septic shock in patients. Methods Sixty patients with septic shock who were admitted to hospital from February 2009 to February 2011 were retrospectively analyzed. According to the death and survival groups, the difference of the basic residual value and the blood lactic acid clearance in the first 24 hours were compared the study. Results The change of alkaline residual value and lactic acid clearance rate in death group were lower than those in survival group (P <0.05). After treatment, the patients with excess of alkali ≤6mmol / L and alkaline excess> 6mmol / L had significantly increased mortality, especially after 24 hours of treatment, the residuals were still ≤6mmol / L and the mortality was as high as92.23%. Conclusion Early alkali surplus contributes to the evaluation of septic shock prognosis and guidance of clinical treatment.