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羟考酮（14-羟基-7，8-二氢可待因酮）自1915年以来在临床上被用作强的阿片激动剂，用于治疗中度和重度疼痛。到目前为止，食物对口服羟考酮生物利用度的影响未见文献报道，本研究目的是为了测定高脂肪食物对羟考团控释片（40mg）和速释液（20mg）的药动学影响。选择正常健康志
Oxycodone (14-hydroxy-7,8-dihydrocodeinone) has been clinically used as a strong opioid agonist since 1915 for the treatment of moderate and severe pain. So far, the influence of food on the oral bioavailability of oxycodone has not been reported. The purpose of this study was to determine the pharmacokinetics of high fat diet on OTC test controlled release tablets (40mg) and immediate-release liquid (20mg) influences. Select normal health blog