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目的探讨脑室内中枢神经细胞瘤临床诊治要点和手术策略。方法回顾性分析我科4年来13例脑室内中枢神经细胞瘤患者的临床表现、影像学检查、病理诊断和治疗效果。结果 13例均行经皮层造瘘脑室入路肿瘤切除术,其中肿瘤全切除9例,近全切除4例。术后颅内感染2例,1例治愈,另1例自动出院后死亡。长期随访11例,术后放疗4例,肿瘤复发后死亡1例。术后并发交通性脑积水行V-P分流术治疗1例。结论中枢神经细胞瘤多发于侧脑室的室间孔附近,熟悉局部的显微解剖并熟练运用显微外科技术争取肿瘤全切除是提高患者预后的关键。未全切患者术后放疗可控制残留肿瘤的生长,延缓复发。
Objective To explore the clinical diagnosis and treatment of intracerebral central neurocytoma and surgical strategies. Methods Retrospectively analyzed the clinical manifestations, imaging examination, pathological diagnosis and treatment of 13 patients with intracranial neuroblastoma in our hospital over the past 4 years. Results Thirteen patients underwent transcortical shunt for ventriculoidectomy, including 9 cases of total tumor resection and 4 cases of total resection. Postoperative intracranial infection in 2 cases, 1 case of cure, the other one died after being discharged automatically. Long-term follow-up of 11 cases, 4 cases of postoperative radiotherapy, tumor recurrence after death in 1 case. Postoperative complications of traffic hydrocephalus V-P shunt in 1 case. Conclusion Central neurocytoma frequently occurs in the lateral ventricle of the interventricular foramen. Familiar with the local micro-anatomy and skilled use of microsurgical techniques for total tumor excision is the key to improve the prognosis of patients. Postoperative radiotherapy can not control the residual tumor growth, delay relapse.