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目的:研究无梗五加果实各提取物的抗疲劳作用,为无梗五加的广泛应用提供依据。方法:采用小鼠力竭游泳实验,考察连续灌胃无梗五加果实提取物2周对小鼠抗疲劳能力的影响,并对给药后小鼠体内血乳酸、血尿素氮、肝糖原和肌糖原的变化进行检测。结果:无梗五加果实提取物能够延长小鼠力竭游泳时间、降低小鼠运动后的乳酸堆积和血尿氮的生成,增加肝糖原、肌糖原的储备量。结论:无梗五加果实具有抗疲劳作用,尤以无梗五加果实醇提物抗疲劳作用最显著。
OBJECTIVE: To study the anti-fatigue effect of each extract of Sessile Pestis fruit and provide the basis for the wide application of Seagame. Methods: The exhaustive swimming test in mice was conducted to investigate the effect of continuous gavage on the anti-fatigue ability of mice after 2 weeks of treatment. The blood lactic acid, blood urea nitrogen, And muscle glycogen changes were detected. Results: The extracts of S. septempunctata could prolong exhaustive swimming time of mice, reduce lactic acid accumulation and formation of hematuria and nitrogen and increase reserve of hepatic glycogen and muscle glycogen. Conclusion: The five non-stemmed fruits have the anti-fatigue effect, especially the anti-fatigue effect of the non-stemmed five-nut fruit alcohol extract is the most obvious.