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目的:探讨早产儿支气管肺发育不良(BPD)的危险因素及预防措施。方法:回顾性分析住院28天以上的早产儿102例,探讨BPD与孕周、出生体重、窒息、吸氧、母亲妊娠并发症、宫内感染性肺炎及机械通气等因素的关系。结果:102例早产儿中BPD者21例,BPD发生率为20.59%(21/102),孕周、出生体重、吸氧浓度>40%的持续时间、宫内感染性肺炎、机械通气及PDA与BPD的发生有关。且吸氧浓度越高,机械通气时间越长,BPD的发生率越高。结论:BPD的发生与孕周、出生体重、吸氧浓度>40%的持续时间、宫内感染性肺炎、机械通气及PDA等因素有关。Logistic回归分析显示宫内感染性肺炎是BPD的独立危险因素。
Objective: To explore the risk factors and preventive measures of bronchopulmonary dysplasia (BPD) in preterm infants. Methods: A retrospective analysis of 102 cases of premature infants hospitalized for more than 28 days was conducted to investigate the relationship between BPD and gestational age, birth weight, suffocation, oxygen inhalation, pregnancy complications, intrauterine infection pneumonia and mechanical ventilation. Results: Of the 102 preterm infants, 21 had BPD, the incidence of BPD was 20.59% (21/102), gestational age, birth weight, the duration of oxygen inhalation> 40%, intrauterine infection pneumonia, mechanical ventilation and PDA And the occurrence of BPD. And the higher the oxygen concentration, the longer the duration of mechanical ventilation, the higher the incidence of BPD. Conclusion: The incidence of BPD is related to gestational age, birth weight, duration of> 40% oxygen inhalation, intrauterine infection pneumonia, mechanical ventilation and PDA. Logistic regression analysis showed that intrauterine infection pneumonia was an independent risk factor for BPD.