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介绍了近年来为增强亚单位疫苗的免疫效果而采取的一些策略和方法,如抗原表位与免疫调节剂的融合、抗原的脂质化修饰、多抗原肽及颗粒化抗原的制备。提示新型亚单位疫苗的研制有赖于多学科理论和技术的发展。
Some strategies and methods adopted to enhance the immune effect of subunit vaccines in recent years are introduced, such as the fusion of epitopes and immunomodulators, the lipid modification of antigens, the preparation of multi-antigen peptides and granulated antigens. Prompted the development of new subunit vaccines depends on the development of multidisciplinary theory and technology.