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目的探讨子宫内膜间质肉瘤的治疗方法。方法回顾性分析12例子宫内膜间质肉瘤患者的临床资料。结果 12例均手术切除,病理诊断为子宫内膜间质肉瘤。术后8例复发,平均复发时间71个月;复发后再次手术4例;复发后全部病例进行了化疗,同时辅以孕激素治疗3例,GnRH治疗1例。同时合并放疗1例,生存38个月。结论子宫内膜间质肉瘤为低度恶性肿瘤,全子宫和双附件切除以及盆腔和腹主动脉旁淋巴结切除术为其基本术式,孕激素治疗应为术后的基本的辅助治疗。
Objective To investigate the treatment of endometrial stromal sarcoma. Methods Retrospective analysis of 12 cases of endometrial stromal sarcoma in patients with clinical data. Results All the 12 cases were surgically removed and pathologically diagnosed as endometrial stromal sarcoma. Eight patients relapsed after operation, with an average recurrence time of 71 months. Four patients underwent reoperation after recurrence. All patients underwent chemotherapy after relapse. Three patients were treated with progestin and one was treated with GnRH. In the meantime, 1 case was combined with radiotherapy and survived for 38 months. Conclusion Endometrial stromal sarcoma is a low-grade malignant tumor, total hysterectomy and double attachment resection and pelvic and para-aortic lymph node dissection as its basic surgical procedures, progestin therapy should be postoperative basic adjuvant therapy.