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目的 观察苦参素与肝动脉插管化疗 (TAE)术治疗中晚期肝癌疗效。方法 75例确诊为中、晚期肝癌患者随机分为治疗组 4 0例和对照组 35例 ,治疗组用苦参素注射液联合肝动脉插管化疗 (TAE)术和对照组用TAE术治疗 ,两组同时加用云芝胞内糖肽胶囊 (云星胶囊 )免疫增强剂口服。结果 治疗 8个月后 ,治疗组改善临床症状 ,提高疗效均明显优于对照组 (P <0 .0 5 ) ,同时副作用明显低于对照组 (P <0 .0 5 ) ,肿瘤退缩率与生存率两组无显著性差异 (P >0 .0 5 )。结论 苦参素能提高介入化疗治疗原发性肝癌中晚期患者的疗效 ,减轻介入化疗的副作用
Objective To observe the curative effect of oxymatrine and hepatic arterial catheterization (TAE) in the treatment of advanced hepatocellular carcinoma. Methods Seventy-five patients diagnosed as intermediate or advanced HCC were randomly divided into treatment group (n = 40) and control group (n = 35). The patients in the treatment group were treated with TAE with kushenin injection and hepatic artery catheterization (TAE) Both groups also added intracellular glycopeptide intracellular polysaccharide capsules (Yunxing capsule) immune enhancer oral. Results After 8 months of treatment, the clinical symptoms and the improvement of the curative effect of the treatment group were significantly better than those of the control group (P0.05), and the side effects were significantly lower than those of the control group (P0.05) There was no significant difference in survival between the two groups (P> 0.05). Conclusion Oxymatrine can improve the efficacy of interventional chemotherapy in the treatment of patients with advanced hepatocellular carcinoma in the advanced stage and relieve the side effects of chemotherapy